- Static methods: Decision Trees (RStudio, Excel®);
- Dynamic methods: Markovian modeling (homogeneous, non-homogeneous), Semi-Markovian modeling, Markov microsimulation model, MCMC, bayesian modeling (RStudio, R, Winbugs, OpenBugs, Python, Excel®), DICE modeling;
- Interactive Modeling : Cost-Effectiveness Model (CEM), Cost-Utility Model (CUM), Budget Impact Model (BIM);
- Quantifying uncertainty of results: deterministic sensitivity analysis (DSA) and probabilistic (PSA) - Simulation of second-order Monte Carlo and Bootstrap techniques.
- Early meeting with HAS / DEAI
- Adapted or de novo medico-economic models for French settings
- Writing of the technical report (cost-effectiveness or cost-utility analysis, budget impact analysis)
- Writing of the CEESP file
- CEESP auditions
Cost-effectiveness ModelingTo estimate an uncertain ex-ante cost-effectiveness of your health technology or innovative treatment (prospective assessment, CEA): Performing the cost-effectiveness acceptability curve (CEAC), the efficiency frontier and positioning the compared strategies with respect to this border. |
Interactive Budget Impact Analysis (IBIA)Assessing the affordability of your innovative product, from the Health insurance perspective. |
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